Very few rappers have taken the game by storm like 50 Cent. He came out the gate aggressive, with the release of “How to Rob,” a hilarious track that dissed every popular rapper at the time, from Jay-Z to Big Pun to the entire Wu-Tang Clan. Rappers didn’t take the song—which was paying homage to The Notorious B.I.G.’s “Just Playing (Dreams)”—as a joke. And 50? He didn’t really care.
If you’re reading this, chances are you know the rest of the story: he got shot nine times, dropped from his label, and basically left for dead. Then, a few years later, he resurfaced, helped invent the modern day mixtape and aligned himself with Dr. Dre and Eminem, releasing Get Rich Or Die Tryin’ in the process.
The best part about 50 is that he never lost that edge—even after becoming the biggest rapper in the world. He kept beefing. There was his infamous blood feud with Murder Inc., of course. But he also went at pretty much every New York rapper making noise at the time.
Now, more than 20 years later and millions up, 50 still hasn’t lost that frenetic energy. He doesn’t rap much anymore, so it’s not coming through in music. Instead, he talks his shit online, going at rappers and celebrity figures on Instagram.
Even as he enters middle age—he just turned 50!—that combative spirit is still alive. Here are 50 Cent’s 50 most chaotic beefs of all time.
Most Brutal 50 Diss: “I’m need my money by Monday.”
If you ask 50, star reporter Meghann M. Cuniff—aka Meghann Thee Reporter—owes him some money. After 50 posted on IG that he’d bet $500k ASAP Rocky would beat his criminal case, Meghann jumped into the comments and said she’d take that bet. Meg was joking. 50 might not have been.
Most Brutal 50 Diss: “Anyway thanks for the invite to your show old billy bobb when we become powerful enough to change the world in conversation Ill stop by lol.”
There was a time when disgraced, right-wing political commentator Bill O’Reilly had beef with essentially every rapper. In the late 2000s, he took aim at 50 Cent after the rapper said there was a chance Obama could be assassinated. O’Reilly called him a “pinhead.” Years later, after 50 criticized O’Reilly and fellow right-wing commentator Laura Ingraham for their remarks about Chris Brown, O’Reilly invited him on his show. 50 passed, robbing the world of another “you mad” moment.
Most Brutal 50 Diss: “Proof you can’t make everybody happy…I love Luenell’s work. That’s why I…put her in Ghost. We saw her big ass was booked already, so we didn’t reach out.”
Last year, 50 Cent hosted Humor & Harmony Festival in Shreveport, Louisiana. Veteran comic Luenell wasn’t on the bill—and she made it known she was disappointed, especially by the lack of women. Of course, 50 didn’t take kindly to the criticism.
Most Brutal 50 Diss: “This is what happens when the “edunacational” system fails you IN THE 50 states of America. LOL.”
50 Cent’s beefs will take you to some unexpected places—like a dust-up with Hurricane Chris, the rapper behind the 2000s hit “A Bay Bay.” Last year, Chris called out Fif for not including any local talent at the aforementioned Humor & Harmony Festival, held in Chris’ hometown. Even if you’re a one-hit wonder, 50 is still going to diss you.
Most Brutal 50 Diss: “I want to punch this nigga nose [Rotimi] got the #1 RNB album time to pay me on gang,”
Should we count this one? We’re not sure. But here’s the backstory: In 2019, 50 Cent relentlessly trolled Rotimi—an artist signed to his label—over money owed to him. At one point, 50 even threatened to punch Rotimi in the face over $300,000. The amount was real, but the threats were fake. It turned out to be a stunt to build awareness around Rotimi’s record and help recoup the money owed.
Most Brutal 50 Diss: “Sometimes you don’t have to say anything at all… Ok, moving right along!”
Desiigner wasn’t happy when 50 Cent, in a very dismissive way, revealed he passed on signing the “Panda” rapper. Desiigner dropped a pretty mid diss in response. 50 fired back by posting a clip of Desiigner’s infamous Funk Flex freestyle.
Most Brutal 50 Diss: “Madonna using rap music for clout on TikTok is pathetic and truly disturbs my spirit…I told y’all grandma was on bullshit like a virgin at 64. LOL.”
At one point, both 50 Cent and Madonna were signed to Interscope and seemed pretty cordial. But their relationship has since devolved, with 50 throwing random shots at her online over the years. To her credit, Madonna hasn’t been shy about swinging back.
Most Brutal 50 Diss: “Shut the fuck up! Let me find out you on one of them tapes, boy.”
You’ve heard the saying: “A friend of my enemy is my enemy.” 50 Cent has lived by that code for years. So when Jason Derulo was asked by TMZ about Diddy’s lawsuits—before the federal indictment—and responded, “Everyone is innocent until proven guilty,” 50 didn’t hesitate.
Most Brutal 50 Diss: “This [ninja] is a strange birdThe fuck is he talking about. I never done nothing but look out for him. If he needed something I gave it to him. I understand now, that shit didn’t matter at all.”
Despite being two of the driving forces behind Power, 50 Cent and Omari Hardwick have a strained relationship. The tension, unsurprisingly, centers around money. Omari has openly expressed feeling underpaid during his time on the show, while 50 has suggested that the actor has an inflated opinion of his own worth.
Most Brutal 50 Diss: “Damn @Kingcombs that what you told Grace O’Marcaigh on that boat huh, gave her the puffy juice with that special sauce in it. LOL BOY OH BOY! BAD BOY FOR LIFE!”
No one has enjoyed Diddy’s legal troubles more than 50 Cent, who has relentlessly mocked his longtime foe for years. So it wasn’t surprising when King Combs released a song with some mild disses aimed at 50. “When all they had was 50 Cent, who put this city on the map? Stop lyin’. Pop’s been hated on by many men and that’s fine,” he raps.
50 didn’t take the lyrics too seriously. Instead, he went to Instagram, writing: “I feel so threatened by the things Christian is saying on his record. I’m afraid for my life, please don’t hurt me, guys. I never mentioned or posted anything about Puffy’s kids because KEEFE D said he killed 2Pac LOL.”
Most Brutal 50 Diss: “[Stoute] was on the air and said, ‘Well, now that he’s not with an actual record company, maybe he can get the record played’…Now it’s playing, Steve. See how your mouth makes things happen?”
A now-famous video from 2014 shows 50 Cent angrily pointing at Steve Stoute during a New York Knicks game. The two had a long history and had once worked together on deals early in 50’s career. But this moment marked a clear breaking point. Just days earlier, Stoute had thrown light shade at 50 during interviews with The Breakfast Club and Hot 97. And 50, being 50, didn’t take kindly to it.
Most Brutal 50 Diss: “Do basement parties then it can still feel like it’s lit I don’t know what to say. LOL get the strap.”
Of course 50 was going to have words for the princess of Murder Inc. During peak beef years, Ashanti caught the wrath of G-Unit. (Lloyd Banks once rapped, “Either I’m blind or Ashanti’s sideburns is thicker than mine.”) In 2007, 50 ran into Ashanti’s now-husband Nelly. Nelly got Fif to apologize. But years later, 50 couldn’t help himself, mocking Ashanti again after she reportedly only sold a few dozen tickets to a show.
Most Brutal 50 Diss: “I ain’t heard from 6ix9ine. He’s his mother’s child now. He told on everybody…He better than Marquise, though. I’ll take him before I take my actual biological son. Fuck that nigga.”
“Have a baby by me, be a millionaire,” might have been an exaggeration from 50. Over the years, he’s had a very public—and at times ugly—back-and-forth with his eldest son, Marquis. In 2013, 50 Cent announced he was taking Marquis out of his will after some damaging text messages between the two were leaked. Marquis later said that 50 had blocked him. Just this past Father’s Day, Marquis blasted 50 again for being an absentee father. Of course, 50 responded on the ‘gram.
Most Brutal 50 Diss: “Wendy williams just told me to get my life together, smh your husband is not a bad man. he deserve a side chick for talking to you, you ugly motherfucker Focus on your own shit bitch. Oh yeah we in club LUST tonight your invited.LOL.”
During her prime, Wendy Williams was known to beef with various rappers. One of her longest-running adversaries was 50, with the two trading various insults for what seems like forever. (She once insinuated he was gay; he, in turn, mocked her appearance and history of drug use.) In 2019, she tried to attend a pool party he was hosting. As one would suspect, she didn’t make it through the doors.
Most Brutal 50 Diss: “The Genius be Socrates, philosophies and hypotheses… I’m like, what the fuck is he talking about?”
One of the more underrated diss records of the 2000s came when GZA took a swing at 50 Cent on “Paper Plates.” The beef had been simmering since 50’s “How to Rob” days, when he dissed the entire Wu-Tang Clan. GZA re-entered the fray in 2007 during a concert, where he called out Soulja Boy, 50, and the overall state of hip-hop. “Paper Plates” was a direct response to an interview where 50 mocked GZA’s dense style of rapping. A quick on wax back-and-forth between the two could have been fun but it never went anywhere after this song.
Most Brutal 50 Diss: “Bitch ass niggas…Makin’ skits, change your voice right, ‘Yo this is Clyde Smith’…Bunch of fuckin’ dirty niggas”
“How to Rob” started a lot of shit, including tension with the entire Wu-Tang Clan. The line that set it off: “I hit the studios, take niggas’ jewels and leave / Catch Rae, Ghost, and RZA for them funny-ass rings.” Rae later responded on the legendary “Clyde Smith” skit on Supreme Clientele, where, using a deep voice, he threatened to send the goons after 50. In response, the rapper would drop the menacing and somewhat underrated “Peace God.”
Most Brutal 50 Diss: “Heard Ghost album them niggas talkin’ that dumb shit duke/I got a shell for every dust-head you run with”
Yes, Rae takes some shots on “Peace God,” but most of the venom is aimed at Ghostface. For years, there were rumors that things got physical between the two, though that never seemed to be the case. By 2009, Ghost confirmed the beef had been squashed, telling XXL: “That’s some old-school shit. Back then, things were all snowballed in the air on some other shit. I didn’t like what he said. That’s where it all started from anyway. But we kicked it on the phone one time, and after we kicked it on the phone, that was it.”
Most Brutal 50 Diss: “Hahahaha, why you make a video like this, man? LOL, I can’t wait to be in the same place with you guys. I know you don’t know about me.”
Not many people are willing to squabble with 50 Cent. One potential take seems to be Stevie J, an original member of the Bad Boys’ production team, the Hitmen. After 50’s relentless jokes and posts targeting Diddy, Stevie fired back, saying he wanted to “shoot the fair one” with 50. The rapper’s response? You guessed it—more jokes.
Most Brutal 50 Diss: “I’m not gonna say anything because I don’t have to. LOL SMH WTF is wrong with these guys?,” 50 responding to a clip of Fredro on Instagram
50 Cent is a sore subject for Onyx rapper Fredro Starr. Over the years, Fredro has gotten visibly animated—and sometimes upset—when asked about 50. The tension stems from an alleged altercation between 50 and Fredro’s crew in the early 2000s, shortly after they appeared together on the song “React.”
Rumors suggest Fredro came out on the losing end; he continues to deny it.
Most Brutal 50 Diss: “Freak bitch look like Kim before the surgery It’s an emergency, for Michael Jackson see,” 50 on “Piggy Bank”
One of Lil’ Kim’s biggest hits is “Magic Stick.” The song features a memorable performance from a then-rising 50 Cent. (The track was actually originally his and featured Trina.) However, things fell apart when they couldn’t complete the music video, and 50 Cent later took shots at Lil’ Kim—first on a freestyle and then on “Piggy Bank.” For years, the issue seemed to cool off but reignited in the early 2020s thanks to 50’s trolling on the ‘gram.
Most Brutal 50 Diss: “The only person that pointed out a million dollars was no money was Damon Dash and he has no money now,” 50 on Million Dollaz Worth of Game
Dame Dash’s financial troubles have been well publicized over the years. So when 50 Cent threw a random shot at Dame while talking with Gillie & Wallo, it sparked a fresh back-and-forth between the two vets. Dame’s a slick talker, but 50 is a master troll.
Most Brutal 50 Diss: “I’m just trying to convince him to take that nigga off the record and just rock, cause his shit is hot. The other shit, we can do without that shit,” 50 during an interview with This Is 50
What once appeared to be an amicable relationship between the two began to sour in the early 2020s, with 50 Cent frequently trolling Jeezy online. Jeezy eventually released a diss track aimed at 50 called “Therapy For My Soul.” A reconciliation seems unlikely. In 2021, while working on the BMF soundtrack, 50 Cent openly stated that he wanted 42 Dugg to remove Jeezy from a song intended for the project.
Most Brutal 50 Diss: “Where is your friend Lisa Bloom now? She ran away and left you smh. You know you done fucked up right! I want Money by Monday,” 50 on Instagram
In 2018, singer Teairra Mari sued 50 Cent for posting a picture from a sex tape involving her and her ex, Akbar Abdul-Ahad that was leaked online. 50 Cent claimed the video was already circulating, and the judge ultimately dismissed the case, ordering her to pay a percentage of his legal fees—about $30,000. Since then, the two have sporadically traded shots at each other, with 50 Cent still trying to collect that $30K.
Most Brutal 50 Diss: “What’s today’s mathematics? Shit ain’t addin’ up/Get knocked with 10 machine guns, only get 12 months/Ooooh weee, don’t talk to me,” 50 on “You So Tough”
When T.I. got caught with a bunch of machine guns by federal agents and only received one year in prison, it raised eyebrows—including those of 50 Cent. The G-Unit leader hinted that T.I. may snitched, even referencing the scenario on “You So Tough.” Their tensions resurfaced years later during the height of Verzuz, when T.I. publicly pushed for a battle with 50.
Most Brutal 50 Diss: “Got damn it. People don’t think you’re gay @meekmillnews they think you on them tapes. Old boy was filming every room, even the toilets,” 50 on Instagram
50 and Meek have been hot and cold for more than a decade. It started back in 2015, when 50 snapped at Meek online after the Philly rapper left a comment under a video of 50 and Yayo. What followed were years of snide remarks, diss tracks, “fuck Meek Mill” chants at concerts, and nonstop trolling on social media.
In 2017, Meek claimed the beef was mostly squashed. But 50 got back on his bullshit when Meek’s name surfaced in the Lil Rod civil lawsuit against Diddy.
Most Brutal 50 Diss: “You make me wanna kiss you like Baby kiss Wayne/ And make you call me daddy like Baby do Wayne/ Damn that shit sounds gay, it’s insane/ I guess that’s the price the lil’ nigga pays for fame,” 50 on “Part Time Lover.”
By the late 2000s, it was clear that Lil Wayne was the best and most popular rapper in the world. One person who had a problem with that was 50 Cent, who started going directly at Wayne. He called him a “whore” for appearing on too many songs and dissed him outright. There was a leaked diss from Wayne and some shots but this beef never really took off. By 2012, 50 was even showing support for Wayne after he suffered a seizure.
Most Brutal 50 Diss: “Kelis said her milkshake bring all the boys to the yard / Then Nas went and tattooed the bitch on his arm,” 50 on “Piggy Bank”
When 50 Cent was coming up, Nas was one of his biggest supporters. Thanks to their mutual connection through the Trackmasters, they collaborated on several tracks, including “Who U Rep With” with Bravehearts and “Too Hot” featuring Nature.
But things got tense after Nas took 50’s spot on Jennifer Lopez’s “I’m Gonna Be Alright” remix. 50 responded with a shot on “Piggy Bank,” and Nas fired back with “MC Burial.” The beef never escalated too far, and it seems they’re in a better place now; the two even reunited on “Office Hours,” one of the better Kings Disease-era songs.
Most Brutal 50 Diss: “JoMo only got one song, Ballin’ written by Max B. Better shut up before I have Tru Life chasing you around the city again. Fucking punk!,” 50 on Instagram
A Cam’ron and 50 Cent interview stirred up tension with Jim Jones, who didn’t appreciate being mentioned by either of them and made that clear. As expected, 50 leaned into the trolling, even suggesting Jimmy might have cooperated with authorities during the 6ix9ine case. The funny part? Cam and 50 were actually talking about Jim standing with Fif during the height of the Dipset beef.
Most Brutal 50 Diss: “While I was out hustling, Banks was more content staying on his porch and watching the world from there… Banks wanted things to come to him, as opposed to going out and getting them for himself,” 50 from Hustle Harder, Hustle Smarter
50’s most talented protégé has built a respectable career as a solid, lyrically driven rapper. But he never became the superstar fans expected when he first entered the scene alongside 50 in the early 2000s. And 50 has consistently pointed this out, often labeling Banks as an underachiever. In his 2020 book Hustle Harder, Hustle Smarter, he was blunt, admitting that while Banks lacked drive, he also blamed himself for not pushing him harder.
Most Brutal 50 Diss: “Oh No!!!, Now she thinks I’m gay because I let her lick my Ass. LMAO. Wait, I didn’t want her to, she forced me, my hands were tied. 50 shades of grey,” 50 on Instagram
One of 50 Cent’s first serious relationships after he blew up was with Vivica Fox. They didn’t last long—only about a year—but the fallout from their relationship has lasted for years. The two haven’t spoken kindly about each other over the years, with 50 Cent claiming early on that she dated him for clout. And Fox trying to insinuate that he was gay.
Most Brutal 50 Diss: “50, don’t call me nigga I don’t wanna talk it out/The .40 cal’ll hit your leg, go on and walk it out/I see it clear, you tryin’ to sabotage Jimmy/See what happens when you talk after sippin’ the Henny?,” 50 on “The Funeral”
Nothing captures the unhinged nature of mid-2000s rap quite like one word: “Curtiiiisss!” 50 Cent and Cam’ron had a short-lived, funny, but not especially memorable rap beef. It started when 50 took shots at rappers signing Koch Records deals, like Jim Jones. Cam jumped in, and the two argued it out live on the radio—back when that kind of thing still happened. 50 responded with “Funeral Music,” which is a good song but light on disses. Cam came back with “Curtis,” powered by that infamous hook. Years later, the two would reminisce about the whole thing in an interview.
Most Brutal 50 Diss: “I think I’m Big Meech,” written under a photo of a rat.
When Big Meech was released from prison in 2024, he publicly linked with Rick Ross. Naturally, that caught 50’s attention (he still hates Ross), and he’s since gone in on Meech, even calling him a snitch. Meech’s son, Lil Meech, has also gotten pulled into the drama, making things messy—especially since 50 was the one who brought the ex–kingpin’s life to the TV screen.
Most Brutal 50 Diss: “I heard Irv trying to sign Shyne, so I ain’t got no love for him /Tell ’em 50 said he soft, he won’t shoot up the club again,” 50 during Funkmaster Flex freestyle
When 50 Cent was on his warpath in the early 2000s, no one was safe—not even Shyne, who was in prison when 50 randomly dissed him during a Funkmaster Flex freestyle. Shyne fired back on “For the Record,” a diss track recorded from a prison phone. Even after his release—and subsequent deportation to Belize—he didn’t let up, going as far as calling 50 a federal agent.
Most Brutal 50 Diss: “French, your shit’s so weak you never had a song by yourself, fool. Ain’t nobody waiting to hear your verse,” 50 on Twitter
In a 2012 interview with this very publication, French Montana lightly criticized 50 Cent’s tendency to start beefs. In response, 50 sparked another long-running feud with the Bronx rapper. To French’s credit, he struck back—adopting the “monkey” insult originally used by Rick Ross. The two eventually squashed the beef years later, with French giving a shoutout to 50’s BMF show.
Most Brutal 50 Diss: “Ay Smurf, don’t think I don’t hear you out there talkin’ about me, you lil dirtbag! Brush your teeth before you talk about me. Wash under your arms, nigga, you smell like Queensbridge,” 50 on “Sleep” (Remix)
“Have Smurf hangin’ out the sunroof to light up your hood, man,” 50 once rapped on “Bump Dat Street Mix.”
Bang Em Smurf was a childhood friend with rap aspirations who was part of the G-Unit circle during the pre-Get Rich or Die Tryin’ days. But things unraveled quickly after Smurf caught a case and 50 refused to pay his $75,000 bail.
In Hustle Harder, Hustle Smarter, 50 explained his reasoning. He enforced a strict no-infighting rule within his crew, and Smurf broke it while on tour. As a result, 50 sent him home and deliberately chose not to bail him out. Smurf didn’t give up on rap, releasing music alongside Domination but he would never pick up much traction outside of beefing with 50. And after serving time for a gun charge, he was deported to Trinidad.
Most Brutal 50 Diss: “Fvck today man the Knicks lost, the pope died, and Kanye told us he sucked his cousin’s d!ck for 8 years. 😴I’m going to bed early tomorrow gotta be a better day,” 50 on Instagram
One of the biggest changing-of-the-guard moments of the last 20 years came in 2007, when 50 Cent and Kanye West decided to release their albums, Curtis and Graduation, on the same day. Going in, 50 was the heavy favorite to debut at No. 1, betting his career on it. But he lost.
Graduation became the bigger moment and signaled that a new era had arrived. Now, Ye is in a very different headspace, and sometimes he plays the agitator. He recently tweeted: “When Graduation dropped, 50 Cent became 25 Cent.”
Most Brutal 50 Diss: “That nigga Buck like Game tell momma he done smoked the TV / I didn’t know he fucked with more dope than BG / Plus a nigga sipped more syrup than Pimp C / Man, keeping these motherfuckers rich ain’t easy,” 50 on “So Disrespectful”
Young Buck was once the Southern face of G-Unit—a talented rapper who dropped two very dope albums under the label. But over the years, he faced tough times, and 50 Cent wasn’t exactly known for showing sympathy. In 2008, 50 famously kicked Buck out of G-Unit and even released audio of the Memphis, Tennessee rapper crying. By the mid-2010s, things looked like they were on the mend, with a reunion in the works. However, they eventually fell out—again—over money, of course.
Most Brutal 50 Diss: “Stay out my mix, Joe, talking about I need therapy. Bitch, you need to stop walking around naked. What the fvck are you doing in the hallway with your balls out, PUNK!,”* 50 on Instagram
Earlier this year, Joe Budden and 50 Cent shared an awkward moment sitting near each other at a Knicks game. Their beef had been simmering for some time, with Budden even threatening a lawsuit over comments 50 made. The tension dates back to the 2000s, when Budden casually threw a line about “fake gangstas” wearing G-Unit shirts during a freestyle, prompting 50 Cent to flip out on him on stage at Summer Jam.
Budden would go on to release the understated diss track “Game Over,” aimed at The Game, which ends with an extended rant that includes the line, “fuck G-Unit.”
Most Brutal 50 Diss: “I ain’t gon’ hold you up. [444] was like golf course music,” 50 on Instagram
For years, 50 Cent and Jay-Z have shared a frenemy-type relationship. It started in the late ’90s when Jay took a couple of subtle jabs at 50 in response to “How to Rob” (“I’m about a dollar, what the fuck is 50 Cent?”). Despite that, there’s usually been a level of mutual respect. They toured together, and Jay eventually jumped on the “I Get Money (Forbes 1-2-3 Remix).” Still, in recent years, their relationship seems distant, with 50 being one of the few major rappers unafraid to shit talk Jay.
Most Brutal 50 Diss: “That fat nigga thought ‘Lean Back’ was ‘In Da Club,’ my shit sold eleven mill’. His shit was a dud,” 50 on “Piggy Bank”
Historically, if you beef with 50 you’re beefing forever. But there have been exceptions—none bigger than Fat Joe. The two now seem genuinely chummy, which is surprising considering how heated things once got. Back in the mid-2000s, they even traded shots live at the MTV Video Music Awards.
Most Brutal 50 Diss: “I just want to tell you what a Psychic told me. I know where your mama work at…now look at her, sleep,” 50 on “A Psychic Told Me”
At the top of 2025, Khaled and 50 played golf together at a celebrity tournament in Florida, officially squashing a beef that stretched back 20 years—one Khaled inherited through his affiliation with Fat Joe and Terror Squad. This one got weird, folks. At one point, there was a tense back-and-forth with Tony Yayo in Miami; and an even odder situation where 50 posted a video of Khaled’s mom sleeping, while reciting a poem called “A Psychic Told Me.” 50 would later reveal that he got the footage from French Montana, before they would get into their own beef.
Most Brutal 50 Diss: “Floyd, will you accept my ALS/ESL challenge? I will donate $750K to a charity of your choice if you can read a full page out of a Harry Potter book out loud without starting, stopping, or fucking up. Lmao,” 50 on Facebook
There was a time when these two were tight. But when Floyd did a short jail stint, 50 got the impression they’d be launching a boxing promotion together. He even signed fighters—like Cuban boxer Yuriorkis Gamboa—in preparation. But once Floyd got out, it became obvious he had no interest in teaming up.
Most Brutal 50 Diss: “Man, I run Interscope, Jada’s tryna annoy me / He’s nothin’ but another disgruntled employee /Been in the game ten years and he still ain’t rich /Even his momma upset that he still ain’t shit,” 50 on “I Run New York”
The 50 Cent vs. The Lox (Jadakiss, Styles P, and Sheek Louch) beef is one of the most underrated rap battles. 50 Cent dropped some cool disses like “Piggy Bank” and “I Run New York,” but The Lox really went crazy here. Songs like “Checkmate,” “Problem Child,” “Sorry Ms. Jackson,” “Bag ‘Em,” and “Shots Fired” are all hard. Years later, 50 Cent would acknowledge Jadakiss for dropping some of the best diss tracks against him.
Most Brutal 50 Diss: “Check this old Jimmy the Rat, speaking about rats—and he’s been telling since the ’80s. We got his paperwork… Kid, stay out of trouble. Don’t end up like old Jimmy the Rat. He thought he was the last Don da da, now he’s making videos from jail with multiple life sentences…,” 50 on Instagram
When it comes to 50 Cent and beef, there’s the music and then there are the streets. One of the ugliest feuds to cross over into real-life violence involved Jimmy Henchman, a street figure who eventually became The Game’s manager. This one got out of hand fast: there was a shootout outside Hot 97; the assault of Henchman’s teenage son, allegedly orchestrated by Tony Yayo and G-Unit affiliate Lowell “Lodi Mack” Fletcher; a drive-by shooting that struck Yayo’s mother’s house; and a planned hit on 50 Cent during the filming of the “I’ll Still Kill” video that never went through. Then, in 2009, Lodi Mack was murdered. More than a decade later, Henchman was sentenced to life plus 30 years for orchestrating the hit.
Most Brutal 50 Diss: “I tell you straight suck a dick / You tryna come with subliminals / Cuz your ass the police / My niggas is criminals,” 50 on “Officer Ricky (Go Head, Try Me)”
50’s battle with Ross was the first real sign that the Queens rapper was slipping. It started when Ross dropped “Mafia Music,” a track that directly dissed 50. In response, 50 went scorched earth—dropping “Officer Ricky,” making countless jokes about Ross, and even flying out the Miami rapper’s baby mother for a shopping spree. But Ross not only survived the barrage—he arguably started making the best music of his career afterward. In fact, the only one who took a real L from this dustup was Gunplay.
Most Brutal 50 Diss: “You said you was gonna see me when your homie got shot / It’s been a while so I’m guessin’ you must’ve forgot / Once again you forget, ain’t this some shit? You forgot about me, bitch I wrote your hits,” 50 on “Love, Hate, Love”
You could argue no one benefited more from 50 Cent than The Game. 50 played a crucial role in Game’s debut The Documentary, helping write six of the album’s songs, including the all time banger “Hate it or Love It.” The album is a G-Unit classic. But their relationship fell apart quickly. After Game tried to distance himself from 50’s many beefs, the G-Unit leader kicked him out of the crew and aired his grievances live on Hot 97. Game pulled up to the station, and a shootout broke out outside. A month later, they publicly squashed the beef, but that was mostly cap. They were soon back dissing each other in songs, videos and even mixtape covers. Please take a look at the cover of G-Unit Radio Part 2 if you haven’t seen it already.
Most Brutal 50 Diss: “I can’t stand that nigga,” 50 in XXL
50 Cent’s beef with Supreme runs deep and, in many ways, casts a shadow over his entire career. Both men come from the same neighborhood—Southside Queens—and one of 50’s most iconic songs, “Ghetto Qur’an,” partially details the story of the Supreme Team. Federal authorities believed Supreme, who was affiliated with Murder Inc., was behind the infamous shooting that left 50 with nine bullet wounds. Supreme is now serving a life sentence. But the feud isn’t over. Supreme’s son has targeted 50 over the years. Just last year, he took aim at 50 on Instagram. And years before, the son posted a picture with Marquise. 50’s response? “If both these little niggaas got hit by a bus, I wouldn’t have a bad day.”
Most Brutal 50 Diss: “He asked to take me shopping. I thought that was the weirdest shit in the world because that might be something that a man says to a woman. And I’m just like, ‘Naw, I’m not fucking with this weird energy or weird shit,” 50 talking with The Hollywood Reporter
50 Cent and Diddy have a long, complicated relationship. For years, it’s been obvious that 50 doesn’t fuck with Diddy. On the other hand, Diddy hasn’t always made his disdain public—but he’s reportedly expressed it privately in allegedly menacing ways.
Throughout Diddy’s lawsuits and the federal investigation, 50 has been all over social media, clowning him and highlighting scandalous headlines. (Even as this is being published, he’s still trolling.) Now, there’s reportedly a Netflix doc on Diddy in the works with 50 Cent producing. So yeah… this one definitely isn’t over.
Most Brutal 50 Diss: “I’m smoking on dat Gotti pack, nah God bless him LOL,” 50 on Instagram
On the CD booklet for Power of the Dollar—50 Cent’s unofficial debut album that was never released—the rapper gives shout-outs to various rappers, labels, and even bootleggers. There’s only one negative message: “fuck all dem Murda Inc. niggas.” The beef with the label founded by Irv Gotti was there from the very start and never let up, fueled by diss tracks, robberies, fights, and even stabbings. Ultimately, 50 got the last laugh. When the Murder Inc. executive passed away last year, 50 took to Instagram to gloat.
Most Brutal 50 Diss: “Maybe I’m so disrespectful ’cause to me you’re a mystery/I know niggas from your hood, you have no history/Never poked nothing, never popped nothing, nigga stop fronting,” 50 on “Back Down”
Odin vs. Loki. Batman vs. Joker. 50 Cent vs. Ja Rule. Some beefs are just forever.Of course, 50 Cent got the better of their early 2000s battle—not only defeating his opponent but also getting rich off a style Ja helped pioneer. But it’s still probably the most mean-spirited rap feud ever. They still don’t like each other. And why would they? This is a beef that’s lasted decades, from real-life scuffles and robberies to on-wax diss records and even concert dates being sabotaged. There’s no chance these two will ever come together and make peace.
